D-Mannose and Urinary Tract Health

We're more than D-mannose

D-Mannose and Urinary Tract Health

Menopause is a natural progression of the women's health journey, and with it comes a multitude of complex changes within the body. One of the biggest changes being bladder and urinary health- Uqora's two favorite topics! Here's everything you need to know so you can make proactive urinary health choices and find peace of mind in the process.

What is D-Mannose?

D-Mannose is a naturally occurring simple sugar, also known as a monosaccharide. Chemically speaking, D-Mannose has the same formula as glucose but with a different atom arrangement. It occurs naturally in the human body, and can also be found in certain types of produce.

How Does D-Mannose Connect to Urinary Health?

D-Mannose has been shown to bind to microorganisms in the urine. So when present in urine, D-Mannose binds to microorganism structures and can help flush them out. Simply put, D-Mannose serves as a decoy, attracting microorganisms, encouraging them to be released through urine.

It’s key to understand that D-Mannose cannot directly kill microorganisms. Thus, D-Mannose is not a replacement for antibiotics or infection treatment. 

Instead, D-Mannose can be taken proactively to promote overall urinary tract health.

What is D-Mannose?

D-Mannose is a naturally occurring simple sugar, also known as a monosaccharide. Chemically speaking, D-Mannose has the same formula as glucose but with a different atom arrangement. It occurs naturally in the human body, and can also be found in certain types of produce.

How Does D-Mannose Connect to Urinary Health?

D-Mannose has been shown to bind to microorganisms in the urine. So when present in urine, D-Mannose binds to microorganism structures and can help flush them out. Simply put, D-Mannose serves as a decoy, attracting microorganisms, encouraging them to be released through urine.

It’s key to understand that D-Mannose cannot directly kill microorganisms. Thus, D-Mannose is not a replacement for antibiotics or infection treatment. 

Instead, D-Mannose can be taken proactively to promote overall urinary tract health.

How the Uqora Regimen Compares to D-Mannose On Its Own:

Uqora Combines D-Mannose With Powerful Ingredients

D-mannose is a powerful mechanism, but it needs to be in the right environment at the right time to fully function. D-Mannose needs to reach the urine to act quickly.

Uqora’s products include additional ingredients that amplify the efficacy of d-mannose in order to tackle urinary health from different angles. That’s why our proactive, three-step approach can help support urogenital health.

How the Uqora Regimen Compares to D-Mannose on its own:

Uqora:
✔️  Binds with microorganisms
✔️ Flushes the urinary tract
✔️ Cleanses biofilm*
✔️ Balances urogenital microbiome**
✔️ Supports bladder wall integrity
 
Uqora:
✔️ Binds to microorganisms
✔️ Flushes the urinary tract
✔️ Cleanses biofilm*
✔️ Balances urogenital microbiome**
✔️ Supports bladder wall integrity
D-Mannose:

✔️ Binds to microorganisms
✔️ Flushes the urinary tract
❌ Cleanses biofilm
❌ Balances urogenital microbiome
❌ Supports bladder wall integrity

 
D-mannose:

✔️ Binds to microorganisms
✔️ Flushes the urinary tract
❌ Cleanses biofilm
❌ Balances urogenital microbiome
Supports bladder wall integrity
 

Where is D-Mannose found?

As D-Mannose is closely related to glucose, it can be found in various fruits such as cranberries, apples, and peaches. Cranberries and cranberry juice are often associated with urinary tract health and are one of the most widely touted natural dietary sources of D-Mannose.

However, there are only trace amounts of D-Mannose present in cranberries.

What Are the Side Effects of D-Mannose?

D-Mannose is generally recognized as safe (GRAS) for the general public by the U.S. FDA when used as directed. D-Mannose in high doses has been linked to minimal side effects in some individuals. Potential side effects include gastrointestinal distress, such as mild cases of diarrhea and bloating.

D-Mannose does not significantly raise blood sugar levels, however, individuals with diabetes should monitor blood sugar levels while taking D-Mannose supplements.

Do Cranberries Contain D-Mannose?

Yes, cranberries contain D-Mannose in low concentrations. The amount of D-Mannose found in cranberries is relatively low compared to related sugars such as fructose and glucose. Only trace amounts of D-Mannose are present in cranberries, so it’s not a high enough dose to support your urinary tract health.

The research behind cranberry for urinary health isn’t super strong. In fact, some research has even found through a series of studies that cranberry products, including cranberry juice, tablets, and capsules, do not significantly reduce the risk of UTIs (2).

While cranberries can be a great addition to a well-balanced diet, we don’t use cranberries in any of our products due to the lack of substantial research.

Where is D-Mannose found?

As D-Mannose is closely related to glucose, it can be found in various fruits such as cranberries, apples, and peaches. Cranberries and cranberry juice are often associated with urinary tract health and are one of the most widely touted natural dietary sources of D-Mannose.

However, there are only trace amounts of D-Mannose present in cranberries.

Do Cranberries Contain D-Mannose?

Yes, cranberries contain D-Mannose in low concentrations. The amount of D-Mannose found in cranberries is relatively low compared to related sugars such as fructose and glucose. Only trace amounts of D-Mannose are present in cranberries, so it’s not a high enough dose to support your urinary tract health.

The research behind cranberry for urinary health isn’t super strong. In fact, some research has even found through a series of studies that cranberry products, including cranberry juice, tablets, and capsules, do not significantly reduce the risk of UTIs (2).

While cranberries can be a great addition to a well-balanced diet, we don’t use cranberries in any of our products due to the lack of substantial research.

What Are the Side Effects of D-Mannose?

D-Mannose is generally recognized as safe (GRAS) for the general public by the U.S. FDA when used as directed. D-Mannose in high doses has been linked to minimal side effects in some individuals. Potential side effects include gastrointestinal distress, such as mild cases of diarrhea and bloating.

D-Mannose does not significantly raise blood sugar levels, however, individuals with diabetes should monitor blood sugar levels while taking D-Mannose supplements.

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Thank you!

My experience with UTIs inspired me to start Uqora

My Experience With UTIs Inspired Me to Start Uqora

In 2018 I had 8 UTIs. I was miserable and desperate for a way to get ahead, but was repeatedly told there was little I could do. This experience inspired me to start Uqora. Built in collaboration with doctors and scientists, Uqora makes UTI relief products and proactive urinary tract supplements so you can finally get ahead. No matter where you are on your urinary health journey, Uqora is here for you. We're so glad you've found us!

— Jenna Ryan, Uqora Co-founder

In 2016 I had 8 UTIs. I was miserable and desperate for a way to get ahead, but was repeatedly told there was little I could do. This experience inspired me to start Uqora. Built in collaboration with doctors & scientists, Uqora makes UTI relief products and proactive urinary tract supplements so you can finally get ahead. No matter where you are on you're urinary health journey, Uqora is here for you. We're so glad you've found us!

— Jenna Ryan, Uqora Co-founder

About our proactive urinary tract products

Urinary Health Support from All Angles

Uqora’s Products leverage D-Mannose and other science-back ingredients so you can finally get proactive about your urinary health.

Each of the products in our Proactive Regimen supports you in a different way, keeping your urinary tract covered from multiple angles. Like D-Mannose, the ingredients in Uqora have been well-researched and were each selected for their unique ability to improve urinary tract health.

Each of the products in our Proactive Regimen supports you in a different way, keeping your urinary tract covered from multiple angles. Like D-Mannose, the ingredients in Uqora have been well-researched and were each selected for their unique ability to improve urinary tract health.

You're not alone.

You're not alone.

We're helping over 400,000 people stay healthy with our three urinary tract products!

We're helping over 400,000 people stay healthy with our three urinary tract products!

References

  1. Ala-Jaakkola, R., Laitila, A., Ouwehand, A.C. et al. Role of D-mannose in urinary tract infections – a narrative review. Nutr J 21, 18 (2022). https://doi.org/10.1186/s12937-022-00769-x, https://nutritionj.biomedcentral.com/articles/10.1186/s12937-022-00769-x#Sec15

  2. Jepson, R. G., Williams, G., & Craig, J. C. (2012). Cranberries for preventing urinary tract infections. The Cochrane database of systematic reviews, 10(10), CD001321. https://doi.org/10.1002/14651858.CD001321.pub5

Ready to get proactive about your urinary health?

Ready to get proactive about your urinary health?

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🌟 Over 20,000 5-star reviews

💸 Money-back guarantee