Supports urinary tract health in the face of everyday life
Cleanses biofilm & keeps your bladder clear daily
Binds with microorganisms in the urine
Supports bladder wall integrity daily
Cleanse biofilm & support bladder wall integrity.
Daily defense to keep your bladder clear and support bladder wall integrity.
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"I love having Uqora in my toolkit for patients struggling with urinary health. Uqora has offered my patients a proactive solution to supporting better urinary health!"
-Dr. Katherine Klos, Board Certified Urologist
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Defend
How much Flush do I need?
If you are not having sex:
Get 10 packets of Flush and drink every 3 days.
If you are sexually active:
Get 20 packets of Flush and drink every 3 days, and immediately after sex.
If you want max support:
Get 30 packets of Flush and drink every day.
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Money-back guarantee
Uqora has a 60-day money-back guarantee. If you're not happy with our products, we'll refund you - no
questions asked.
Flexible schedule
Manage your shipment dates and the products you’re subscribed to.
Renewal notifications
We always send email notifications a few days before your order renews.
Easy cancellation
If for some reason you need to cancel, we make sure the process is hassle-free. Plus, there are never
any penalties for cancelling.
Why Defend?
Defend is one part of our 3-part proactive regimen, recommended for anyone impacted by urinary health 3 times or more a year. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. It also supports bladder wall integrity. You can take Defend by itself, but we recommend everyone looking for better urinary health also take Flush (our drink mix). Bundle the two here.
Antibiotic-free
Gluten-free
Find out more about Defend
All about Defend
Each bottle includes a 1-month supply (60 capsules). Take 2 capsules together with water daily.
Mechanism research on the ingredients in Defend shows their ability to cleanse biofilm. Defend also supports bladder wall integrity. With these two functions, Defend helps to keep your bladder clean in the face of hard-to-pinpoint things like stress, hormonal changes and holding your bladder.
Biofilm is a collection of microorganisms bound together that attaches to surfaces, like the bladder wall. Mechanism research on the ingredients in Defend shows their ability to clean biofilm.
Defend's science and ingredients
Uqora Defend includes multiple active ingredients, which all play an important role:
Piperine is the “active” compound in black pepper. Oddly enough, Piperine can increase the bioavailability of curcumin by 2,000%! Typically, curcumin has poor bioavailability, meaning our bodies don’t absorb the ingredient well on its own. Uqora Defend includes black pepper powder in a small dose to enable our bodies to better absorb curcumin.
D-Mannose is a type of carbohydrate that occurs naturally in small quantities in many fruits and vegetables including apples, peaches, green beans, and broccoli. D-Mannose is an important part of human metabolism and urinary health. It has been shown to bind to microorganisms and flushes them from the urinary tract.
This extract is mostly (95%) made up of micronutrients in green tea leaves called catechins, like EGCG and EGC. These have been the subject of much research on various health benefits and have antioxidant properties. Along with curcumin, catechins have been shown to cleanse biofilm in preliminary laboratory research. The green tea extract in Uqora Defend is from the leaves of green tea plants.
Turmeric Root Extract (95% Curcuminoids) is the “active” compound in turmeric, a flowering plant commonly used as a spice that is a member of the ginger family. Turmeric Root Extract gives Uqora Defend its yellowish color. Biofilm can build-up in the urinary tract and turmeric root extract (along with the polyphenols from green tea) has been shown to cleanse biofilm in preliminary laboratory research. The curcumin in Uqora Defend is extracted from the turmeric root.
We recommend talking with your physician if you’re pregnant, nursing, take blood thinners or have a history of liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
42% of all adults in the U.S. are Vitamin D deficient. The vitamin D in Defend is vitamin D3, also called cholecalciferol, the form of vitamin D made by the skin when exposed to sunlight. New research shows that Vitamin D supplementation increases tight junction proteins in the bladder. Essentially, these proteins connect cells that are next to each other.
Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you maximum urinary support. Flush (our drink mix) flushes the urinary tract, Defend cleanses biofilm from the urinary tract and supports bladder wall integrity, and Promote helps maintain healthy vaginal bacteria. Get the Complete Regimen here.
Defend is one part of our 3-part proactive regimen. It’s designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and it also supports bladder wall integrity. You can take Defend by itself, but we recommend that everyone looking for better urinary health also take Flush (our drink mix). Bundle the two here.
Defend and Flush contain different active ingredients. While the two products are complementary, they don’t have the same function. Defend is designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and supporting bladder wall integrity. Flush (our drink mix) flushes the urinary tract when you need support, like after sex, with the right amount of effective ingredients. For more support, we recommend bundling the two here.
Uqora Defend is not vegan because the vitamin D is sourced from sheep's wool. We chose this source because it is the same version used in clinical research, and we wanted to ensure the maximum efficacy. We apologize for how this may affect our vegan customers.
The recommended daily upper limit for vitamin D is 4000 IU. Most vitamin D supplements have <2000 IU, and Uqora Defend now includes 1500 IU. So, most people should be in the clear, but if you are currently taking other vitamin D sources be sure to check the volume. We've included that amount to be close to the clinical research amounts but not have a full 2000 IU in case people are supplementing with vitamin D that goes up to 2000 IU to stay at a lower dosage of 3,500 per day.
Supplement facts
Caution Statements
Caution: consult your physician before use if pregnant, nursing, taking medication including blood thinners or have a history of kidney, liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
Hear what our community has to say
Click the link below to read stories from our customers. We stay out of it! These reviews are unfiltered and uncurated.
“My goal is to ensure the scientific integrity of the ingredients and product function and to keep pushing innovation through research in the urinary health space.”
Your well being is our #1 priority. If Uqora doesn’t work for you, we’ll give you your money back.
And we promise our customer success team will make it easy. We pride ourselves on having a responsive, caring team full of real people ready to answer all your questions and help in any way.
From our founder:
I had 8 UTIs in one year…
“I was stuck in the cycle of UTIs for years. I was desperate for a way to get ahead, but was told there was little I could do. This inspired my husband and I to start Uqora, alongside doctors & scientists. Now, we’ve been able to help over 500,000 people and counting. Ready to give us a try?”
We recommend Flush because you want better urinary tract health.
Flush is a drink mix that proactively flushes the urinary tract. Ingredients help to alkalize the urine, plus binds to microorganisms in the urine and flushes them from the urinary tract.
Try risk free with our 60 day money back guarantee!
We recommend Defend because you said urinary tract health affects you 3+ times a year. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. It also supports bladder wall integrity.
(Psst, we really recommend you also try Flush (our drink mix) to flush your urinary tract in addition to Defend since you’re frequently affected by urinary tract health. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
Promote is formulated with clinically studied ingredients, including lactoferrin and two strains of “good” lactic acid-producing bacteria. These ingredients work together to support a balanced vaginal microbiome. Plus, Promote helps maintain a healthy vaginal pH with a fast-acting formula that reduces itching and discharge in as little as 15 days, providing lasting benefits throughout the month. †
(Psst, if you also struggle with urinary health issues, we recommend trying Flush, our drink mix, which is essential for ongoing urinary health support.)
Try risk-free with our 60-day money-back guarantee!
Flush, because you want better urinary tract health.
Flush is a drink mix that flushes the urinary tract. Drink Flush every 3 days and immediately after sex, if sexually active.
Defend, because you said urinary tract health affects you 3+ times a year. Defend supports bladder wall integrity and continually cleanses biofilm, which is key for day-to-day urinary tract health. Take two capsules a day.
Try risk free with our 30 day money back guarantee!
Flush, because you want better urinary tract health.
Flush is a drink mix that flushes the urinary tract. Drink Flush every 3 days and immediately after sex, if sexually active.
Promote, because sex and hormonal changes (especially menopause) affect your vaginal microbiome, and can impact urinary tract health.
Promote is a vaginal probiotic formulated with clinically studied ingredients. These ingredients work together to support a balanced vaginal microbiome—which is key, since vaginal health and urinary health is tightly linked. †
(Psst, we really recommend you try Defend in addition to Promote & Flush since you want better urinary tract health. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
Defend, because you said urinary tract health affects you 3+ times a year. Defend cleanses biofilm, according to mechanism research, and supports bladder wall integrity, which is key for day-to-day urinary tract health. †
Promote, because you want to support your vaginal health. †Promote is a vaginal probiotic formulated with clinically studied ingredients. These ingredients work together to support a balanced vaginal microbiome—a key component of urinary tract health. †
(Psst, we really recommend you try Flush to flush your urinary tract in addition to Promote & Defend since you’re frequently affected by urinary tract health. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
We recommend In Control Bladder Support to help maintain healthy bladder function.
Formulated with a scientifically tested and clinically studied blend of herbal ingredients, this daily supplement helps reduce urinary urgency, frequency, & occasional accidents or leaks associated with normal aging to provide you with 24-hour support. Results in as little as 2 weeks, with greatest results at 8 weeks.
Try risk-free with our 60-day money-back guarantee!
60-Day Money-Back Guarantee
FSA/HSA eligible
