Flush Advanced+ & Defend
Flush Advanced+ & Defend
Two layers of daily urinary tract support:
- Flush Advanced+ helps reduce the risk of recurrent UTIs in healthy women ‡
- Defend cleanses biofilm & supports bladder wall integrity*†
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FSA/HSA eligible

Learn more about each product in your bundle
Flush Advanced+
Flush Advanced+
Clinically shown to reduce the risk of recurrent UTIs‡
- Effectively flushes microorganisms from the urinary tract.†
- Fast acting & long lasting: D-mannose works quickly, while whole-fruit cranberry offers sustained activity. Together, they help to support urinary health throughout the day with continued use.†‡
- Provides immune support with 5x the recommended daily value of Vitamin C.†
In a clinical trial, 500mg Pacran resulted in:
58% relative risk reduction in recurrent UTIs vs placebo‡
‡See below for the relationship between cranberry consumption and UTIs
Defend
Defend
Supports bladder wall integrity and cleanses biofilm†
- Helps cleanse biofilm*, the collection of microorganisms that attach to surfaces
- Supports bladder wall integrity* for ongoing urinary health
- Includes science-backed ingredients: Turmeric Root Extract, Green Tea Extract (EGCG), Vitamin D, and D-Mannose
*according to mechanism research
Flush Advanced+ Regimen Reviews
Below is a place for our customers to share stories. We stay out of it! These reviews are unfiltered and uncurated.
Uqora's dietary supplement products are not intended to diagnose, treat, cure or prevent disease. Results may vary.
- DGDeborah G.Verified BuyerI recommend this productRated 5 out of 5 stars2 days agoLess trips
The new drink has helped with the amount of trips to bathroom. Glad I changed.
Was this helpful? - COCharna O.Verified BuyerI recommend this productRated 5 out of 5 stars6 days agoHealing !
Since I been using Uquora and other supplements I find the difference. I haven’t had a UTI in two months . I’m very pleased. Thank you .
Was this helpful? - COCharlotte O.Verified BuyerI recommend this productRated 5 out of 5 stars2 weeks agoOne year in the clear
Before I started UQORA Flush and Defend, I had 5 UTIs in an 11 month stretch of time. It was so discouraging to be on antibiotics so many timesI I take 2 Defend every morning and mix up the good-tasting flush powder with water every 2nd or 3rd day. Much to my delight, I have not had a UTI for one year now. I’m sticking with UQORA from here on out. The price is reasonable compared to all the pain and suffering I endured 5 times last year. I highly recommend this product!
Was this helpful? - PRPatrick R.Verified BuyerI recommend this productRated 4 out of 5 stars3 weeks agoRelief!
I wasn't sure if anything would help but Uqora flush has. No more discomfort and I didn't need antibiotics. The Defend I should have taken but delayed it . I now have begun the defend to hopefully prevent further frequent uti.
Was this helpful? - ASAmanda S.Verified BuyerI recommend this productRated 5 out of 5 stars3 weeks agoSo helpful!
After my hysterectomy I began to get a UTI just about every three months. I decided to give uqora a try. It’s been 6 months since I started it and I haven’t had any UTIs. To say I’m very happy with Uqora is an understatement! Thanks Uqora!!
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FAQs
How is Flush Advanced+ different from regular cranberry supplements?
Flush Advanced+ is a dual-action formula that goes beyond cranberry, combining it with D-mannose to help flush the urinary tract and give you more complete support. Flush Advanced+ contains 500mg of Pacran whole fruit cranberry powder per serving. This clinical dosing helps reduce the risk of recurrent UTIs in healthy women with daily consumption‡. It is not recommended to exceed once daily dosing of Flush Advanced+ or to combine it with regular Flush. If you’re ever not sure what’s right for you, always consult with your doctor.
Can I take Flush Advanced+ and Defend in the same day?
Yes. Flush Advanced+ and Defend are designed to be taken together. It doesn’t matter what time of day you take them, but consistency is key to success. We recommend taking the products at whatever time works best for you.
For best results, be sure to take the products as directed.
How is Flush Advanced+ different from regular Flush?
Flush Advanced+ is a dual-action formula with two clinically dosed ingredients: D-mannose and whole-fruit cranberry powder. By using the entire cranberry—skin, seeds, flesh, and juice—we take a whole-fruit approach that keeps natural compounds working together to help support urinary tract health. Combining cranberry with D-mannose provides both fast-acting and long-lasting activity to support urinary health throughout the day with continued use. It’s especially suited for those dealing with recurrent UTIs‡. Regular Flush, on the other hand, contains only D-mannose, offering quick urinary tract flush support without the added benefits of cranberry.
Try Uqora for 60 days, risk-free.
We’re confident in our products and we want you to feel confident trying them, too. If you’re not satisfied with your results, simply reach out within 60 days of purchase for a full refund. We’re here to support you.
5 star brand reviews
Discover why so many recommend Uqora for effective, lasting relief.
Jenna Ryan
Uqora Co-Founder
“I was stuck in the cycle of
UTIs for years.”
“I was stuck in the cycle of UTIs for years.”
Jenna Ryan, Uqora Co-Founder
Founded by a chronic UTI sufferer, at Uqora, we get it. That’s why we always lead with empathy and authenticity to connect and humanize this highly stigmatized issue.
Meet the doctors and scientists helping Uqora make a difference
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Dr. Alyssa Dweck
Board-certified Gynecologist; CMO Bonafide Health, LLC
"Sexual health and general health go hand in hand; urinary tract health has always been vital for my gynecologic patients."
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Dr. Payal Bhandari
Integrative Functional Medicine Physician
"Urinary health is all about being proactive so you can easily take the steps which help you stay healthy."