Money-back guarantee

Money-back guarantee

Uqora has a 60-day money-back guarantee. If you're not happy with our products, we'll refund you - no questions asked.

Flexible schedule

Flexible schedule

Manage your shipment dates and the products you’re subscribed to.

Renewal notifications

Renewal notifications

We always send email notifications a few days before your order renews.

Easy cancellation

Easy cancellation

If for some reason you need to cancel, we make sure the process is hassle-free. Plus, there are never any penalties for cancelling.

Defend

Learn more about Defend

Defend

Daily urinary health support

Not everything clears on its own. Biofilm can remain by attaching to surfaces, making it harder to fully clear over time. Ingredients in Defend work to cleanse biofilm and support bladder wall integrity* for ongoing urinary tract health.

What is biofilm?

Biofilm is a collection of microorganisms bound together that can attach to tissue.

Biofilm can shield microorganisms from your body’s own defense systems and can remain in place over time.

Defend includes ingredients studied for their ability to help cleanse biofilm*, and supports bladder wall integrity* for a healthier urinary tract environment.

* Based on mechanism research

Defend key ingredients

Turmeric Root Extract

Green Tea Extract (EGCG)

Vitamin D

D-Mannose

Defend | Supplement facts

See supplement  facts

Defend | Caution statements

Caution: consult your physician before use if pregnant, nursing, taking medication including blood thinners or have a history of kidney, liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.

Directions

  • Take two capsules daily with water
  • Use consistently for ongoing urinary tract support
FAQs

What is biofilm?

Does Uqora have caffeine in it?

Why are Uqora Defend capsules orange?

What’s the difference between In Control and Defend?

What is biofilm?

Biofilm is a collection of microorganisms bound together (in a matrix) that attaches to surfaces.

Does Uqora have caffeine in it?

Green tea leaf extract is an ingredient in Defend, but the caffeine is removed during the extraction process, leaving only a small amount. This small amount is unlikely to have a stimulating effect, but individuals who are highly sensitive to caffeine may prefer to take Defend earlier in the day.

Why are Uqora Defend capsules orange?

The orange color you're seeing is curcumin powder, one of the ingredients in Defend. Due to the natural properties of curcumin, slight color variations can occur from month to month — this is completely normal!

What’s the difference between In Control and Defend?

In Control is for bladder control support and Defend is for proactive urinary tract health. 

In Control uses clinically-studied ingredients to help with occasional overactive bladder and urinary incontinence due to normal aging. If you experience urinary urgency, frequency, leaks or nighttime bathroom trips, we recommend In Control to support healthy bladder function. 

If you struggle with recurring urinary tract issues, we recommend Defend as part of our proactive urinary tract health regimen. Ingredients in Defend help cleanse biofilm* (an unwanted buildup of microorganisms that can attach to tissue) while also supporting bladder wall integrity* for daily urinary tract support.

BUY NOW

You're not alone.

Uqora has helped 700,000+ people.

  • Teresa D.
    Five stars reviews  Verified Purchase
    Life saver

    I will probably be a lifetime subscriber! Defend has helped me tremendously.

  • Kamille T.
    Five stars reviews  Verified Purchase
    Exceptional products

    Overall experience was exceptional. The products really work. Thank you so much for developing a real solution that actually works. Will return again!!

  • Carmen P.
    Five stars reviews  Verified Purchase
    Product and service

    Product has worked great (taking it over one year). Customer service is outstanding.

  • Chris C.
    Five stars reviews  Verified Purchase
    Excellent product

    This has been a great addition to my daily routine! I take it every day and it really does make a difference!

  • Wanda M.
    Five stars reviews  Verified Purchase
    Thank you Uqora!

    It was good. Team with Uqora is awesome. Everything that is advertised is as they say.

  • Ruth S.
    Five stars reviews  Verified Purchase
    Uqora

    Great things couldn’t be any better.Thanks to you Uqora!

  • Stacey G.
    Five stars reviews  Verified Purchase
    A++

    Great I've telling people how good this product works!

1 of 7

Get our
maximum support

Try the new Flush Advanced+ Regimen

Urinary tract flush powered by whole fruit cranberry & D-mannose

Cleanse biolfilm*

Vaginal probiotic

Shop Now

Get our
maximum support

Get results or your money back.

If you don’t experience the results you expect, simply reach out within 60 days of purchase, and we’ll refund your purchase—no hassle, no questions. We’re here to support.

TRY RISK FREE
Five stars
36,321

5 star brand reviews

Discover why so many recommend Uqora for effective, lasting relief.

Jenna Ryan

Uqora Co-Founder

I was stuck in the cycle of UTIs for years.”

Jenna Ryan, Uqora Co-Founder

Founded by a chronic UTI sufferer, at Uqora, we get it. That’s why we always lead with empathy and authenticity to connect and humanize this highly stigmatized issue.

BUY NOW
  • Dr. Alyssa Dweck

    Board-certified Gynecologist; CMO Bonafide Health, LLC

    "Sexual health and general health go hand in hand; urinary tract health has always been vital for my gynecologic patients."

  • Dr. Payal Bhandari

    Integrative Functional Medicine Physician

    "Urinary health is all about being proactive so you can easily take the steps which help you stay healthy."

  • Dr. Katherine Klos

    Board-certified Urologist

    "I believe in urinary health management that moves away from reaction and works toward proactive care."

1 of 3

Add Flush for just $15!

  • Drink to flush your urinary tract when you need extra support.
  • Gives a boost after things like sex, exercise, travel, or holding your bladder.
LEARN MORE

Life’s too short to be put on hold by UTIs. We’re here to help.

Your well-being is our #1 priority. Our customer success team is here to ensure you have the best experience possible. We’re a team of real people— ready to answer your questions, and offer support every step of the way.

CONTACT US

Defend Reviews

Below is a place for our customers to share stories. We stay out of it! These reviews are unfiltered and uncurated.

Uqora's dietary supplement products are not intended to diagnose, treat, cure or prevent disease. Results may vary.

reviews
4.8
Rated 4.8 out of 5 stars
Based on 4,235 reviews
Total 5 star reviews: 3.8k Total 4 star reviews: 189 Total 3 star reviews: 97 Total 2 star reviews: 50 Total 1 star reviews: 108
94%would recommend these products
4,235 reviews
  • CH
    Charlotte H.
    Verified Buyer
    Reviewing
    Defend
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Defend

    I have been using your product for several months . I had a UTI but I was on it only a few weeks. So far it seems to be working.

  • AP
    Allison P.
    Verified Buyer
    Reviewing
    Defend
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Working well

    This product is working well to control my occasional incontinence. Thanks Uqora!

  • PH
    Patricia H.
    Verified Buyer
    Reviewing
    Defend
    I recommend this product
    Rated 5 out of 5 stars
    21 hours ago
    Defender

    Defender has been a game changer for my over active bladder and IC…I added Defender to my urologists prescription…the 2 together have slowed my need to go so often… I have a monthly subscription for Defender…my urologist said all of the natural ingredients in Defender would be good for me. He had no idea about Uqora products… he knows now !

  • JB
    Julie B.
    Verified Buyer
    Reviewing
    Defend | 3 month supply
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Life saver

    Since I have been using Uqora, I went from dealing with UTI's almost every month to none. That's right! Zero!

  • AS
    Andy S.
    Verified Buyer
    Reviewing
    Defend | 3 month supply
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Convenient

    We like the three month supply format; would never go back to monthly.