Flush & Defend

2174 reviews

Flush your urinary tract, cleanse biofilm and support bladder wall integrity.

Includes 1 month supply of Defend (take daily) and 10, 20, or 30 packets of Flush (pink lemonade flavor).

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Flush & Defend

Why Flush & Defend?

Flush and Defend are key components of our 3-part proactive regimen. This bundle is recommended for anyone impacted by urinary health 3 or more times a year. Flush your urinary tract with Flush, cleanse biofilm & support bladder wall integrity with Defend. This bundle is a great combination if you are already taking a high-quality vaginal probiotic. If you aren't, we recommend getting the Complete Regimen, which includes Promote, here.

Antibiotic-free

Gluten-free

Find out more about each product in your bundle:

Click to learn about each of them below.

All about Flush

  • Mix one packet in 8-12 ounces of water. Drink Flush every 3 days and after sex.

  • Flush has 2 flavor options - unflavored and a mild pink lemonade flavor.

  • Flush's ingredients work quickly to gently flush the urinary tract. Special ingredients alkalize the urine, making it less acidic, unlocking the power of d-mannose. At the same time, Flush’s ingredients take effect upon urination, and deliver immune support.

  • If you are not having sex: Get 10 packets of Flush and drink every 3 days.

    If you are sexually active: Get 20 packets of Flush and drink every 3 days, and immediately after sex.

    If you want maximum support: Get 30 packets of Flush and drink every day.

Flush's science and ingredients

Uqora Flush includes multiple active ingredients, which all play an important role:

Calcium is an ion that acts as an electrolyte. Calcium comes from our diet, and is required for a range of things, including bone production and strengthening, proper nerve function, and muscle function. In Uqora Flush, calcium is included in a salt form with ascorbate, called calcium ascorbate. When in fluid, these salts dissolve into calcium and ascorbate ions. Calcium intake needs to keep up with or exceed calcium loss in the urine in order to maintain proper bone mineralization and hydration.

Citric acid is a weak acid commonly found in many fruits. Despite being an acid, it has an alkalizing effect on the urine, meaning it makes the urine less acidic. Citric acid, along with the natural lemon flavor, gives Uqora Flush its sour citrus taste. *Pink Lemonade Flavor Only

D-Mannose is a type of carbohydrate that occurs naturally in small quantities in many fruits and vegetables including apples, peaches, green beans, and broccoli. D-Mannose is an important part of human metabolism and urinary health. It has been shown to bind to microorganisms and flushes them from the urinary tract.

Magnesium is another essential nutrient lost during urination. It is required for hundreds of functions in the body, including the creation of DNA. The magnesium in Uqora Flush is in the form of magnesium ascorbate (the magnesium salt of Vitamin C) and magnesium carbonate (the salt of magnesium and carbonate, which is used to carbonate water).

Citrate is the salt form of citric acid. In Uqora Flush, we have potassium citrate. When mixed in water, potassium citrate dissolves into potassium and citrate ions. Potassium citrate has an alkalizing effect on the urine, meaning it makes the urine less acidic. Potassium ions are required for proper hydration and replace the potassium lost during urination.

Vitamin B6 refers to a group of compounds that enable proper protein, carbohydrate, and fat metabolism. The form of Vitamin B in Uqora Flush is called pyridoxine hydrochloride. Pyridoxine is found in many common plant foods like pistachios and cacao. Vitamin B6 is an essential nutrient, meaning that people need to obtain it from the diet to live. Vitamin B6 is water-soluble and excreted in the urine. Its involvement with many interactions in the body, make it foundational to whole body health.

The form of Vitamin C found in Uqora Flush is called ascorbate. Ascorbate is the non-acidic salt of ascorbic acid. Vitamin C is also an essential nutrient, and is required for many processes in the body, including immune system function. It is an antioxidant, which provides protective benefits in the human body and is excreted in the urine. Vitamin C has been studied for its positive effects on the immune
system.

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Unflavored supplement facts

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Common questions about Flush

Yes, many of our customers drink Flush daily. To be extra safe, we recommend you don’t exceed taking more than 3 individual packets per day.

We do not recommend drinking Flush while on antibiotics because Flush contains potassium and it may be important to limit potassium intake while on some antibiotics. You should begin Flush as soon as you have completed your antibiotics. Keep in mind, Uqora’s products are not a treatment.

Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you maximum urinary support. Flush (our drink mix) flushes the urinary tract, Defend cleanses biofilm from the urinary tract and supports bladder wall integrity, and Promote helps maintain healthy vaginal bacteria. Get the Complete Regimenhere.

Flush is one part of our 3-part proactive regimen because it is beneficial for anyone looking for better urinary health. Our signature drink mix is an easy, effective way to flush your urinary tract on a regular basis. Flush can be taken by itself but we do recommend adding Defend if you’re regularly affected by urinary tract health. Bundle the two here.

All about Defend

  • Each bottle includes a 1-month supply (60 capsules). Take 2 capsules together with water daily.

  • Mechanism research on the ingredients in Defend shows their ability to cleanse biofilm. Defend also supports bladder wall integrity. With these two functions, Defend helps to keep your bladder clean in the face of hard-to-pinpoint things like stress, hormonal changes and holding your bladder.

  • Biofilm is a collection of microorganisms bound together that attaches to surfaces, like the bladder wall. Mechanism research on the ingredients in Defend shows their ability to clean biofilm.

Defend's science and ingredients

Uqora Defend includes multiple active ingredients, which all play an important role:

Piperine is the “active” compound in black pepper. Oddly enough, Piperine can increase the bioavailability of curcumin by 2,000%! Typically, curcumin has poor bioavailability, meaning our bodies don’t absorb the ingredient well on its own. Uqora Defend includes black pepper powder in a small dose to enable our bodies to better absorb curcumin.

D-Mannose is a type of carbohydrate that occurs naturally in small quantities in many fruits and vegetables including apples, peaches, green beans, and broccoli. D-Mannose is an important part of human metabolism and urinary health. It has been shown to bind to microorganisms and flushes them from the urinary tract.

This extract is mostly (95%) made up of micronutrients in green tea leaves called catechins, like EGCG and EGC. These have been the subject of much research on various health benefits and have antioxidant properties. Along with curcumin, catechins have been shown to cleanse biofilm in preliminary laboratory research. The green tea extract in Uqora Defend is from the leaves of green tea plants.

Turmeric Root Extract (95% Curcuminoids) is the “active” compound in turmeric, a flowering plant commonly used as a spice that is a member of the ginger family. Turmeric Root Extract gives Uqora Defend its yellowish color. Biofilm can build-up in the urinary tract and turmeric root extract (along with the polyphenols from green tea) has been shown to cleanse biofilm in preliminary laboratory research. The curcumin in Uqora Defend is extracted from the turmeric root.


We recommend talking with your physician if you’re pregnant, nursing, take blood thinners or have a history of liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.

42% of all adults in the U.S. are Vitamin D deficient. The vitamin D in Defend is vitamin D3, also called cholecalciferol, the form of vitamin D made by the skin when exposed to sunlight. New research shows that Vitamin D supplementation increases tight junction proteins in the bladder. Essentially, these proteins connect cells that are next to each other.

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Common questions about Defend

Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you maximum urinary support. Flush (our drink mix) flushes the urinary tract, Defend cleanses biofilm from the urinary tract and supports bladder wall integrity, and Promote helps maintain healthy vaginal bacteria. Get the Complete Regimen here.

Defend is one part of our 3-part proactive regimen. It’s designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and it also supports bladder wall integrity. You can take Defend by itself, but we recommend that everyone looking for better urinary health also take Flush (our drink mix). Bundle the two here.

Defend and Flush contain different active ingredients. While the two products are complementary, they don’t have the same function. Defend is designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and supporting bladder wall integrity. Flush (our drink mix) flushes the urinary tract when you need support, like after sex, with the right amount of effective ingredients. For more support, we recommend bundling the two here.

Uqora Defend is not vegan because the vitamin D is sourced from sheep's wool. We chose this source because it is the same version used in clinical research, and we wanted to ensure the maximum efficacy. We apologize for how this may affect our vegan customers. All of the other ingredients in Defend are vegan, as well as all of the ingredients in Flush and Promote.

The recommended daily upper limit for vitamin D is 4000 IU. Most vitamin D supplements have <2000 IU, and Uqora Defend now includes 1500 IU. So, most people should be in the clear, but if you are currently taking other vitamin D sources be sure to check the volume. We've included that amount to be close to the clinical research amounts but not have a full 2000 IU in case people are supplementing with vitamin D that goes up to 2000 IU to stay at a lower dosage of 3,500 per day.

Add Promote for just $12

  • 3 strains of lactobacillus (aka 'good' vaginal bacteria)
  • Key to helping maintain healthy vaginal bacteria.
  • Supports a healthy urinary tract
Learn More

From our founder:
I had 8 UTIs in one year…

“I was stuck in the cycle of UTIs for years. I was desperate for a way to get ahead, but was told there was little I could do. This inspired my husband and I to start Uqora, alongside doctors & scientists. Now, we’ve been able to help over 500,000 people and counting. Ready to give us a try?”

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Flush & Defend Reviews

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Uqora's dietary supplement products are not intended to diagnose, treat, cure or prevent disease. Results may vary.