A clear plastic jar with pills and a 'Uqora Defend' label, and a plastic pill bottle with a 'Uqora Promote' label
Uqora Defend and Promote Supplement Facts
5-star customer review, Defend, Promote
Pink Lemonade Unflavored. Defend key ingredients, vitamin 3, green tea extract, turmeric root extract, biofilm.
Pink Lemonade Unflavored. List of Promote's key ingredients.
A clear plastic jar with pills and a 'Uqora Defend' label, and a plastic pill bottle with a 'Uqora Promote' label
Uqora Defend and Promote Supplement Facts
5-star customer review, Defend, Promote
Pink Lemonade Unflavored. Defend key ingredients, vitamin 3, green tea extract, turmeric root extract, biofilm.
Pink Lemonade Unflavored. List of Promote's key ingredients.

Defend & Promote

Defend & Promote

4.9
Rated 4.9 out of 5 stars
5,359 Reviews

Cleanse biofilm* and support bladder wall integrity*, and help maintain healthy vaginal bacteria. †

Contains 1 month supply (1 bottle each, take daily).

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  • Renews every 4 weeks

One time purchase $60 $54.99

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How much Flush do I need?

If you are not having sex:

Get 10 packets of Flush and drink every 3 days.

If you are sexually active:

Get 20 packets of Flush and drink every 3 days, and immediately after sex.

If you want max support:

Get 30 packets of Flush and drink every day
Money-back guarantee

Money-back guarantee

Uqora has a 60-day money-back guarantee. If you're not happy with our products, we'll refund you - no questions asked.

Flexible schedule

Flexible schedule

Manage your shipment dates and the products you’re subscribed to.

Renewal notifications

Renewal notifications

We always send email notifications a few days before your order renews.

Easy cancellation

Easy cancellation

If for some reason you need to cancel, we make sure the process is hassle-free. Plus, there are never any penalties for cancelling.

Defend
Promote

Learn more about each product in your bundle:

Defend

Daily urinary health support

Defend provides daily, proactive support for a healthy bladder and urinary tract. Ingredients in our formula work to cleanse biofilm* while also supporting bladder wall integrity for on-going urinary health. †

* Based on mechanism research

Defend key ingredients

Turmeric Root Extract

Green Tea Extract (EGCG)

Vitamin D

D-Mannose

Defend | Supplement facts

See supplement facts

Defend | Caution statements

Caution: consult your physician before use if pregnant, nursing, taking medication including blood thinners or have a history of kidney, liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
Directions

  • Take two capsules daily with water
  • Use consistently for ongoing urinary tract support †
FAQs

What is biofilm?

Does Uqora have caffeine in it?

Why are Uqora Defend capsules orange?

What is biofilm?

Biofilm is a collection of microorganisms bound together (in a matrix) that attaches to surfaces.

Does Uqora have caffeine in it?

Green tea leaf extract is an ingredient in Defend, but the caffeine is removed during the extraction process, leaving only a small amount. This small amount is unlikely to have a stimulating effect, but individuals who are highly sensitive to caffeine may prefer to take Defend earlier in the day.

Why are Uqora Defend capsules orange?

The orange color you're seeing is curcumin powder, one of the ingredients in Defend. Due to the natural properties of curcumin, slight color variations can occur from month to month — this is completely normal!

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Promote

Vaginal Microbiome Support

Promote is a vaginal probiotic formulated with clinically studied ingredients to support a balanced vaginal microbiome—because vaginal health and urinary tract health are tightly linked.

This fast-acting formula helps maintain healthy bacteria and yeast levels, reducing symptoms in just 15 days. †

Promote key ingredients

Lactobacillus acidophilus & Lacticaseibacillus rhamnosus: "Good" bacteria that naturally release lactic acid to help balance vaginal pH †

Lactoferrin: A protein that works with lactic acid bacteria to promote a healthy vaginal microbiome †

Promote | Supplement facts

See supplement facts

Promote | Caution statements

Caution: Consult with your physician before use if pregnant, nursing or taking medication.
Directions

  • Take one capsule daily with water for 15 consecutive days
  • Probiotics will continue to colonize the vagina after 15 days
  • Restart the 15-day regimen each month to maintain benefits
FAQs

How does Promote help with urinary health?

Does Promote help with digestion?

What is lactoferrin?

Can I take Promote if I am lactose intolerant?

Why aren't there more strains in Promote?

How does Promote help with urinary health?

Promote is a clinically studied 15-day formula which includes lactoferrin and 2 strains of “good” bacteria. Lactoferrin works with the lactic acid bacteria to promote a healthy vaginal microbiome – which is key since vaginal health & urinary health are tightly linked. †

Does Promote help with digestion?

No, Promote is a probiotic designed for vaginal health, not digestive health. Not all probiotics are the same, as there are many different types of lactic acid bacteria. The specific types of lactic acid bacteria in Promote are intended to colonize the vagina and provide vaginal health benefits. †

What is lactoferrin?

Lactoferrin is a protein that works together with good lactic acid producing bacteria to support a healthy vaginal microbiome. By promoting a balanced vaginal environment, lactoferrin aids lactic acid bacteria in reducing itching and discharge, providing month-long comfort for your vaginal health. †

Can I take Promote if I am lactose intolerant?

One ingredient in Promote, Lactoferrin, is derived from milk. Reactions to different milk-derived ingredients may vary based on a person's sensitivity to lactose. Promote has never been specifically studied in those with lactose intolerance. Therefore, we recommend that individuals with lactose intolerance concerns speak to their healthcare practitioner before taking Promote.

Why aren't there more strains in Promote?

We’ve included the strains plus lactoferrin shown to maintain vaginal health and have decided to not include anything extra. Why? Microbiomes are sensitive ecosystems, and we believe it is better to not include strains with unknown impact.

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Get results or your money back.

If you don’t experience the results you expect, simply reach out within 60 days of purchase, and we’ll refund your purchase—no hassle, no questions. We’re here to support.

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Five stars
36,321

5 star brand reviews

Discover why so many recommend Uqora for effective, lasting relief.

read all reviews

Jenna Ryan

Uqora Co-Founder

“I was stuck in the cycle of UTIs for years.”

Jenna Ryan, Uqora Co-Founder

Founded by a chronic UTI sufferer, at Uqora, we get it. That’s why we always lead with empathy and authenticity to connect and humanize this highly stigmatized issue.

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Meet the doctors and scientists helping Uqora make a difference

  • Dr. Alyssa Dweck

    Board-certified Gynecologist

    "Sexual health and general health go hand in hand; urinary tract health has always been vital for my gynecologic patients."

  • Dr. Payal Bhandari

    Integrative Functional Medicine Physician

    "Urinary health is all about being proactive so you can easily take the steps which help you stay healthy."

  • Dr. Katherine Klos

    Board-certified Urologist

    "I believe in urinary health management that moves away from reaction and works toward proactive care."

  • Dr. Susan Mitmesser

    Chief Science Officer

    “My goal is to ensure the scientific integrity of the ingredients and product function and to keep pushing innovation through research in the urinary health space.”

1 4
MEET OUR ADVISORS
Uqora Complete Regimen, Pink Lemonade Flavored Flush, Defend, and Promote

Add Flush for just $13

  • Drink to flush your urinary tract when you need extra support.
  • Gives a boost after things like sex, exercise, travel, or holding your bladder.
LEARN MORE

Life’s too short to be put on hold by UTIs. We’re here to help.

Your well-being is our #1 priority. Our customer success team is here to ensure you have the best experience possible. We’re a team of real people— ready to answer your questions, and offer support every step of the way.

CONTACT US

Defend & Promote Reviews

Below is a place for our customers to share stories. We stay out of it! These reviews are unfiltered and uncurated.

Uqora's dietary supplement products are not intended to diagnose, treat, cure or prevent disease. Results may vary.

reviews
4.9
Rated 4.9 out of 5 stars
Based on 5,359 reviews
Total 5 star reviews: 5k Total 4 star reviews: 211 Total 3 star reviews: 91 Total 2 star reviews: 52 Total 1 star reviews: 49
96%would recommend this product
Write a Review (Opens in a new window)
5,359 reviews
  • HE
    Helena E.
    Verified Buyer
    I recommend this product
    Age Range 71-80
    Rated 5 out of 5 stars
    21 seconds ago
    Preventive care

    After finally being taken off of antibiotics (5years), my urologist's PA suggested I take defend and promote daily, along with estradiol 3 days a week for preventive care. Hopefully, I will still be infection free at my November appointment.

    Was this helpful?
  • CD
    Coleen D.
    Verified Buyer
    I recommend this product
    Age Range 51-60
    Rated 5 out of 5 stars
    3 minutes ago
    Finally consistent relief!

    Thank goodness my neurologist provided me with a coupon for Uqora!! After struggling for years with repeated UTIs that were extremely uncomfortable and required two different series of antibiotics to treat, I am finally experiencing consistent relief. I use the Defend and Promote package and the liquid flush. IN combination, taking routinely, these products keep me UTI-free. Do yourself a favor and try them out and then keep taking it! Whenever my routine is interrupted, I inevitably end up with problems. I just put it on auto subscription and stick to it!

    Was this helpful?
  • SE
    Susan E.
    Verified Buyer
    I recommend this product
    Age Range 71-80
    Rated 5 out of 5 stars
    17 minutes ago
    No more infections!

    I used to have an infection every 2 months

    And one turned septic and landed me in the hospital.

    No more infections with uqora

    Was this helpful?
  • JT
    Joann T.
    Verified Buyer
    I recommend this product
    Age Range 61-70
    Rated 5 out of 5 stars
    42 minutes ago
    No UTI s

    Since starting Uqora I have not had a UTI since June 2024.

    Could not be more pleased after suffering 6 UTI s in 2023

    Was this helpful?
  • EA
    ELVA A.
    Verified Buyer
    I recommend this product
    Age Range 71-80
    Rated 5 out of 5 stars
    1 hour ago
    Continued Relief

    I am thankful for this treatment program that has helped me prevent

    multiple UTI infections.

    Was this helpful?