Cleanse biofilm and support bladder wall integrity, and support your vaginal health. †
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"I love having Uqora in my toolkit for patients struggling with urinary health. Uqora has offered my patients a proactive solution to supporting better urinary health!"
-Dr. Katherine Klos, Board Certified Urologist
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Defend & Promote
How much Flush do I need?
If you are not having sex:
Get 10 packets of Flush and drink every 3 days.
If you are sexually active:
Get 20 packets of Flush and drink every 3 days, and immediately after sex.
If you want max support:
Get 30 packets of Flush and drink every day.
Money-back guarantee
Uqora has a 60-day money-back guarantee. If you're not happy with our products, we'll refund you - no
questions asked.
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Manage your shipment dates and the products you’re subscribed to.
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We always send email notifications a few days before your order renews.
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any penalties for cancelling.
Why Defend & Promote?
Defend and Promote are key components of our 3-part proactive regimen. This bundle is recommended for anyone who is impacted by urinary health 3 or more times and looking to support their vaginal health. Defend cleanses biofilm and supports bladder wall integrity, while Promote supports vaginal health—crucial for maintaining both vaginal and urinary health. For maximum support, we recommend the Complete Regimen, which includes Flush, here.
Antibiotic-free
Gluten-free
Customer support that cares
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Find out more about each product in your bundle:
Click to learn about each of them below.
All about Defend
Each bottle includes a 1-month supply (60 capsules). Take 2 capsules together with water daily.
Mechanism research on the ingredients in Defend shows their ability to cleanse biofilm. Defend also supports bladder wall integrity. With these two functions, Defend helps to keep your bladder clean in the face of hard-to-pinpoint things like stress, hormonal changes and holding your bladder.
Biofilm is a collection of microorganisms bound together that attaches to surfaces, like the bladder wall. Mechanism research on the ingredients in Defend shows their ability to clean biofilm.
Defend's science and ingredients
Uqora Defend includes multiple active ingredients, which all play an important role:
Piperine is the “active” compound in black pepper. Oddly enough, Piperine can increase the bioavailability of curcumin by 2,000%! Typically, curcumin has poor bioavailability, meaning our bodies don’t absorb the ingredient well on its own. Uqora Defend includes black pepper powder in a small dose to enable our bodies to better absorb curcumin.
D-Mannose is a type of carbohydrate that occurs naturally in small quantities in many fruits and vegetables including apples, peaches, green beans, and broccoli. D-Mannose is an important part of human metabolism and urinary health. It has been shown to bind to microorganisms and flushes them from the urinary tract.
This extract is mostly (95%) made up of micronutrients in green tea leaves called catechins, like EGCG and EGC. These have been the subject of much research on various health benefits and have antioxidant properties. Along with curcumin, catechins have been shown to cleanse biofilm in preliminary laboratory research. The green tea extract in Uqora Defend is from the leaves of green tea plants.
Turmeric Root Extract (95% Curcuminoids) is the “active” compound in turmeric, a flowering plant commonly used as a spice that is a member of the ginger family. Turmeric Root Extract gives Uqora Defend its yellowish color. Biofilm can build-up in the urinary tract and turmeric root extract (along with the polyphenols from green tea) has been shown to cleanse biofilm in preliminary laboratory research. The curcumin in Uqora Defend is extracted from the turmeric root.
We recommend talking with your physician if you’re pregnant, nursing, take blood thinners or have a history of liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
42% of all adults in the U.S. are Vitamin D deficient. The vitamin D in Defend is vitamin D3, also called cholecalciferol, the form of vitamin D made by the skin when exposed to sunlight. New research shows that Vitamin D supplementation increases tight junction proteins in the bladder. Essentially, these proteins connect cells that are next to each other.
Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you maximum urinary support. Flush (our drink mix) flushes the urinary tract, Defend cleanses biofilm from the urinary tract and supports bladder wall integrity, and Promote helps maintain healthy vaginal bacteria. Get the Complete Regimen here.
Defend is one part of our 3-part proactive regimen. It’s designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and it also supports bladder wall integrity. You can take Defend by itself, but we recommend that everyone looking for better urinary health also take Flush (our drink mix). Bundle the two here.
Defend and Flush contain different active ingredients. While the two products are complementary, they don’t have the same function. Defend is designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and supporting bladder wall integrity. Flush (our drink mix) flushes the urinary tract when you need support, like after sex, with the right amount of effective ingredients. For more support, we recommend bundling the two here.
Uqora Defend is not vegan because the vitamin D is sourced from sheep's wool. We chose this source because it is the same version used in clinical research, and we wanted to ensure the maximum efficacy. We apologize for how this may affect our vegan customers.
The recommended daily upper limit for vitamin D is 4000 IU. Most vitamin D supplements have <2000 IU, and Uqora Defend now includes 1500 IU. So, most people should be in the clear, but if you are currently taking other vitamin D sources be sure to check the volume. We've included that amount to be close to the clinical research amounts but not have a full 2000 IU in case people are supplementing with vitamin D that goes up to 2000 IU to stay at a lower dosage of 3,500 per day.
Supplement facts
Caution Statements
Caution: consult your physician before use if pregnant, nursing, taking medication including blood thinners or have a history of kidney, liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
All about Promote
Each bottle includes 15 capsules (1-month supply). Take 1 capsule orally with water for 15 consecutive days each month. The remainder of the month will be capsule-free. Each month, restart the 15-day dosing to maintain month-long support. †
Promote is a clinically studied 15-day formula which includes lactoferrin and 2 strains of “good” bacteria. Lactoferrin works with the lactic acid bacteria to promote a healthy vaginal microbiome – which is key since vaginal health & urinary health are tightly linked. †
Not all probiotics are the same. Promote is a vaginal probiotic, not a digestive probiotic. Promote supports the good bacteria that are specific to the vagina. You can take Promote alongside other probiotics you might be taking.
Promote contains clinically-studied ingredients, including lactoferrin and 2 strains of "good" lactic acid bacteria, that work together to promote a healthy vaginal microbiome. Plus, Promote helps maintain a healthy vaginal pH with a fast-acting formula that reduces itching & discharge in just 15 days, lasting all month long! †
Promote's science and ingredients
Uqora Promote includes multiple active ingredients, which all play an important role:
Lactobacillus Acidophilus & Lacticaseibacillus Rhamnosus are 2 specific types of “good” bacteria that support vaginal health. When consumed orally, these bacteria travel from the gut to the vagina, where they can populate. Promote helps maintain this healthy vaginal bacteria, which is a key component of urinary tract health.
Lactoferrin is a protein that works together with good lactic acid bacteria to support a healthy vaginal microbiome. By promoting a balanced vaginal environment, lactoferrin aids lactic acid bacteria in reducing itching and discharge, providing month-long comfort for your vaginal health. †
Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you with our maximum support. Flush’s (our drink mix) D-mannose works to flush the urinary tract. Flush also delivers immune support. Ingredients in Defend cleanse biofilm according to mechanism research and includes vitamin D to help support bladder wall integrity. Promote’s ingredients supply “good” lactic acid bacteria plus lactoferrin that support vaginal health. This is key since vaginal health and urinary health are connected. Get the Complete Regimen here.
One ingredient in Promote, Lactoferrin, is derived from milk. Reactions to different milk-derived ingredients may vary based on a person's sensitivity to lactose. Promote has never been specifically studied in those with lactose intolerance. Therefore, we recommend that individuals with lactose intolerance concerns speak to their healthcare practitioner before taking Promote.
No. Promote is a probiotic designed for vaginal health, not digestive health. Not all probiotics are the same, and there are many different types of lactobacillus, and they live in different parts of the body. The types of lactobacillus in Promote are specific to the vagina.
Lactoferrin is a protein that works together with good lactic acid bacteria to support a healthy vaginal microbiome. By promoting a balanced vaginal environment, lactoferrin aids lactic acid bacteria in reducing itching and discharge, providing month-long comfort for your vaginal health.
We’ve included the strains shown to maintain vaginal health and have decided to not include anything extra. Why? Microbiomes are sensitive ecosystems, and we believe it is better to not include strains with unknown impact.
Supplement facts
Caution Statements
Caution: Consult with your physician before use if pregnant, nursing or taking medication.
Hear what our community has to say
Click the link below to read stories from our customers. We stay out of it! These reviews are unfiltered and uncurated.
“My goal is to ensure the scientific integrity of the ingredients and product function and to keep pushing innovation through research in the urinary health space.”
Your well being is our #1 priority. If Uqora doesn’t work for you, we’ll give you your money back.
And we promise our customer success team will make it easy. We pride ourselves on having a responsive, caring team full of real people ready to answer all your questions and help in any way.
From our founder:
I had 8 UTIs in one year…
“I was stuck in the cycle of UTIs for years. I was desperate for a way to get ahead, but was told there was little I could do. This inspired my husband and I to start Uqora, alongside doctors & scientists. Now, we’ve been able to help over 500,000 people and counting. Ready to give us a try?”
We recommend Flush because you want better urinary tract health.
Flush is a drink mix that proactively flushes the urinary tract. Ingredients help to alkalize the urine, plus binds to microorganisms in the urine and flushes them from the urinary tract.
Try risk free with our 60 day money back guarantee!
We recommend Defend because you said urinary tract health affects you 3+ times a year. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. It also supports bladder wall integrity.
(Psst, we really recommend you also try Flush (our drink mix) to flush your urinary tract in addition to Defend since you’re frequently affected by urinary tract health. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
Promote is formulated with clinically studied ingredients, including lactoferrin and two strains of “good” lactic acid-producing bacteria. These ingredients work together to support a balanced vaginal microbiome. Plus, Promote helps maintain a healthy vaginal pH with a fast-acting formula that reduces itching and discharge in as little as 15 days, providing lasting benefits throughout the month. †
(Psst, if you also struggle with urinary health issues, we recommend trying Flush, our drink mix, which is essential for ongoing urinary health support.)
Try risk-free with our 60-day money-back guarantee!
Flush, because you want better urinary tract health.
Flush is a drink mix that flushes the urinary tract. Drink Flush every 3 days and immediately after sex, if sexually active.
Defend, because you said urinary tract health affects you 3+ times a year. Defend supports bladder wall integrity and continually cleanses biofilm, which is key for day-to-day urinary tract health. Take two capsules a day.
Try risk free with our 30 day money back guarantee!
Flush, because you want better urinary tract health.
Flush is a drink mix that flushes the urinary tract. Drink Flush every 3 days and immediately after sex, if sexually active.
Promote, because sex and hormonal changes (especially menopause) affect your vaginal microbiome, and can impact urinary tract health.
Promote is a vaginal probiotic formulated with clinically studied ingredients. These ingredients work together to support a balanced vaginal microbiome—which is key, since vaginal health and urinary health is tightly linked. †
(Psst, we really recommend you try Defend in addition to Promote & Flush since you want better urinary tract health. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
Defend, because you said urinary tract health affects you 3+ times a year. Defend cleanses biofilm, according to mechanism research, and supports bladder wall integrity, which is key for day-to-day urinary tract health. †
Promote, because you want to support your vaginal health. †Promote is a vaginal probiotic formulated with clinically studied ingredients. These ingredients work together to support a balanced vaginal microbiome—a key component of urinary tract health. †
(Psst, we really recommend you try Flush to flush your urinary tract in addition to Promote & Defend since you’re frequently affected by urinary tract health. Find that bundle here.)
Try risk free with our 60 day money back guarantee!
We recommend In Control Bladder Support to help maintain healthy bladder function.
Formulated with a scientifically tested and clinically studied blend of herbal ingredients, this daily supplement helps reduce urinary urgency, frequency, & occasional accidents or leaks associated with normal aging to provide you with 24-hour support. Results in as little as 2 weeks, with greatest results at 8 weeks.
Try risk-free with our 60-day money-back guarantee!
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